John Handley High School is a member of the Northwestern District, Region 4C, and Class AAAA of the Virginia High School League (VHSL), Inc. The Northwestern District comprises the following schools: John Handley, James Wood, Millbrook, Sherando, Fauquier, Liberty-Bealeton, Kettle Run. Region 4C is a combination of the Northwestern District and the Dulles District in Loudoun County. The VHSL Class AAAA includes Region 4A, 4B, 4C, and 4D.
John Handley High School has a rich history of athletic success; collecting 49 State Championships, 31 State Runner Ups and 78 Region Championships since its founding in 1923.